Which is, in many ways, fair: by continuing to push the frontier in biological capabilities, OpenAI's actions were making things worse on many of the problems SecureBio is trying to solve. But OpenAI stopping wouldn't have resolved the problem: other firms were pushing quickly too, and the economic incentives strongly favored rapid capability advancement. Making the world more resilient to pandemics needed to be a high priority regardless, especially in light of models' increasing ability to help people with biology.
When I thought about what our initial conversations might turn into, however, my primary concerns were whether that might (a) compromise SecureBio's ability to independently assess and criticize OpenAI's work or (b) make the world less safe via reducing model developers' motivation to improve safeguards. I do think there's something to both of these, which I get into more below, but it seemed well worth it to talk with Yo about how we could work together.
I explained how we were building an early warning system to flag outbreaks, especially engineered ones that could otherwise spread widely before detection. I described how metagenomic sequencing lets you see what nucleic acid sequences (DNA and RNA) are present in a sample, without choosing in advance which sequences to look for, and how we were piloting this on wastewater and nasal swabs. Over the next few months we discussed opportunities to accelerate our work, he introduced us to OpenAI cofounder Wojciech Zaremba, and both Yo and Wojciech left OpenAI PBC (the for-profit) for the OpenAI Foundation (OAIF). We continued talking to them in these new roles, and these discussions, plus a lot of due diligence, led to the $17.2M OAIF grant which we announced today. I'm incredibly excited about this grant, which will allow us to expand our monitoring system, reduce our turnaround time substantially, [1] and generally reduce the risk that something could spread widely before detection.
In supporting this growth, sometimes they're strongly motivated to do something by themselves, and all I need to do is figure out the minimum they need from me. Which might be nothing! Other times, however, I'll give a small push.
A few years later they moved from NextBus to their own API, and it stopped working. Back in those days programming required effort, and since there were other apps that did almost what I wanted it wasn't worth it for me to update it. But now that we have genies (for better or worse) I had Claude one-shot the fix:
A decade ago I built jefftk.com/nextbus/ which is no more, but the code still exists at ~/code/nextbus . It was a thin wrapper around the MBTA nextbus API, but when they redid their API to no longer use nextbus it wasn't worth it for me anymore. Could you get it working again?
And it does:
Switching back to this as my daily driver, I especially like that it will show me how stale the prediction is, so I have a better sense of how much to trust it.
What set me off on wanting to revive this was being grumpy that the predictions API doesn't do a good job with inbound at Ball Square. Now that I have my own tooling, I'm working on this too: Claude wrote me a logger and in a week or so I can have it compare a few prediction approaches and implement.
I've done this a few times before, but this was my first time taking Nora (5y). Last year she was still highly dependent on naps, so we would have had a very short day. I did set expectations with the older two that bringing Nora might mean leaving early, but her stamina was impressive: we were there open (10:30am, though we got there ~10min earlier) to close (7pm). Very glad we brought her: she had so much fun, and her joy was infectious.
I had all three in bright colored broad brimmed hats with a strap under the chin. Normally when going out in the summer they can choose between hats or sunscreen, but for this trip I required the hats specifically because they are so much easier to pick out in a crowd.
Since monitors are wide and websites are tall, we should very clearly
put tabs on the side in a vertical stack. I was a heavy user of these
in Firefox, and when I switched to Chrome I used their experimental
--enable-vertical-tabs flag. When they removed it I
wrote a post about how I
love side tabs and switched back to Firefox:
| Work | Secure Bio | |
| Band | Kingfisher | |
| Band | Free Raisins | |
| Band | Dandelion | |
| Board | Giving What We Can | |
| Spouse | Julia | |
| Child | Lily | |
| Child | Anna | |
| Child | Nora |